MiRCancer : a microRNA-cancer association database and toolkit based on text mining / by Boya Xie.
| Author/creator | Xie, Boya |
| Other author | Ding, Qin. |
| Other author | East Carolina University. Department of Computer Science. |
| Format | Theses and dissertations |
| Publication Info | [Greenville, N.C.] : East Carolina University, 2010. |
| Description | 51 pages : illustrations (some color), digital, PDF file |
| Supplemental Content | Access via ScholarShip |
| Subjects |
| Summary | MicroRNAs (miRNAs) are a class of single-stranded small non-coding RNAs. Study of miRNAs has been a fast growing field since the first miRNA was discovered in 1993. Many findings indicate that miRNA plays an important role in regulating crucial processes in gene development. In this research, we designed and implemented a framework called miRCancer, which is the first comprehensive database for miRNA expression profiles in human cancers based on experimental results. miRCancer also includes an integrated microRNA sequence analysis toolkit to help researchers discover possible relationships and functionalities of miRNAs. Text mining was used to automatically extract miRNA expression information from online electronic literatures. A new coding system, EICD-O, was introduced to annotate miRNA expressions in cancers. |
| General note | Presented to the faculty of the Department of Computer Science. |
| General note | Advisor: Qin Ding. |
| General note | Title from PDF t.p. (viewed April 25, 2011). |
| Dissertation note | M.S. East Carolina University 2010. |
| Bibliography note | Includes bibliographical references. |
| Technical details | System requirements: Adobe Reader. |
| Technical details | Mode of access: World Wide Web. |
Availability
| Library | Location | Call Number | Status | Item Actions |
|---|---|---|---|---|
| Electronic Resources | Access Content Online | ✔ Available |