Effects of inhibitors on fumarate reductase in anaerobic mitochondria from rangia cuneata mantle / by Robert Earl Beasley.
| Author/creator | Beasley, Robert Earl author. |
| Other author | Ito, Takeru, degree supervisor. |
| Other author | East Carolina University. Department of Biology. |
| Format | Theses and dissertations |
| Production | 1979. |
| Description | 49 leaves : illustrations ; 28 cm |
| Supplemental Content | Access via ScholarShip |
| Subjects |
| Summary | Light and electron micrographs of the mantle of Rangia cuneata, the common east and gulf coast clam, showed that distribution of mitochondria in this tissue appeared to be much lower than that in most aerobic organisms. The NADH fumarate reductase, the electron transport components which catalyze anaerobic oxidation of NADH in the presence of the terminal electron acceptor fumarate, was present in the mantle mitochondria of this organism. The NADH fumarate reductase was sensitive to both rotencne and malonate, and thus considered to comprise at least NADH dehydrogenase and succinic dehydrogenase. All attempts to demonstrate coupled phosphorylation with the NADH fumarate reductase failed, which had been postulated to occur in considerable extent in many obligate and facultative anaerobes. The failure appeared to be due to the isolated mitochondria probably being in a highly uncoupled and disrupted state. |
| Local note | Joyner-"Presented to the faculty of the Department of Biology ... in partial fulfillment of the requirements for the degree Master of Science in Biology." |
| General note | Presented to the Faculty of the Department of Biology. |
| General note | Advisor: Takeru Ito |
| Dissertation note | M.S. East Carolina University |
| Bibliography note | Includes bibliographical references (leaves 47-49). |
| Genre/form | Academic theses. |
| Genre/form | Academic theses. |
| Genre/form | Thèses et écrits académiques. |
Availability
| Library | Location | Call Number | Status | Item Actions |
|---|---|---|---|---|
| Joyner | University Archives | ASK AT SPECIAL COLLECTIONS DESK | ✔ Available | Request Material |
| Electronic Resources | Access Content Online | ✔ Available |