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LEADER 03040cam a2200385Ia 4500

005 20141212020424.0;

008 040712s2005 njua b 001 0 eng ;

010 a| 2004016130;

020 a| 1588291995 :c| $119.60;

035 a| (Sirsi) H1033805;

035 a| (OCoLC)55955455;

049 a| NEHH;

245 00 a| Molecular neurosurgery with targeted toxins /c| edited by Ronald G. Wiley and Douglas A. Lappi.;

300 a| xi, 311 pages :b| illustrations ;c| 24 cm;

336 a| text2| rdacontent;

337 a| unmediated2| rdamedia;

338 a| volume2| rdacarrier;

504 a| Includes bibliographical references and index.;

505 0 a| Introduction to molecular neurosurgery / Ronald G. Wiley and Douglas A. Lappi -- Ribosome-inactivating proteins / Fiorenzo Stirpe -- Biochemical, physiological, and behavioral characterizations of the cholinergic basal forebrain lesion produced by 192 IgG-saporin / Jerene J. Waite -- Basal forebrain cholinergic lesion by 192 IgG-saporin: a tool to assess the consequences of cortical cholinergic dysfunction in Alzheimers disease / Reinhard Schliebs -- 192 IgG-saporin-induced partial cortical cholinergic deafferentation as a model for determining the interactions between brain aging and neurodevelopmental defects in the cortical cholinergic input system / Martin Sarter and John P. Bruno -- Exploring the role of acetylcholine in primate cognition using Me20.4 IgG-saporin / Rosalind M. Ridley and Harry F. Baker -- Cortical cholinergic deafferentation induces A-beta deposition: towards a physiologic animal model of Alzheimer's disease / Thomas G. Beach ... [et al.] -- Chemical dissection of brain glucoregulatory circuitry / Sue Ritter ... [et al.] -- Cardiovascular deficits after lesions of C1 adrenergic neurons with a saporin-based immunotoxin / Patrice G. Guyenet, Ruth L. Stornetta, and Ann M. Schreihofer -- Saporin conjugates and pain / Ronald G. Wiley and Douglas A. Lappi -- The use of saporin conjugates to dissect neurons responsible for sleep and wakefulness / Carlos Blanco-Centurion ... [et al.] -- Isolectin I-B4-mediated cytotoxic targeting of sensory neurons / Lucy Vulchanova and Christopher N. Honda -- B fragment of cholera toxin conjugated to saporin / Peter T. O'hara, Kanwarjit Kelley, and Luc Jasmin.;

650 12 a| Immunotoxinsx| therapeutic use.=| ^A942793;

650 22 a| Antibodies, Monoclonalx| therapeutic use.=| ^A922995;

650 22 a| Cholinergic Fibersx| metabolism.=| ^A943314;

650 22 a| Neurobiologyx| methods.=| ^A924887;

650 22 a| Neuronsx| pathology.=| ^A943315;

700 1 a| Wiley, Ronald G.,d| 1947-=| ^A943316;

700 1 a| Lappi, Douglas A.=| ^A943317;

994 a| C0b| NEH;

919 a| BOOK;

959 a| 1033805;

096 a| QW 630.6 I3 M718 2005;

596 a| 4;

998 a| 1568914;

999 a| QW 630.6 I3 M718 2005w| NLMc| 1i| 31740008343232d| 2/1/2011e| 8/24/2005f| 2/1/2011g| 1l| HSLBKm| HSLn| 1p| $119.60r| Ys| Yt| HBKu| 7/5/2005x| BOOKz| HSTACKSo| .STAFF. 0;

Molecular neurosurgery with targeted toxins / edited by Ronald G. Wiley and Douglas A. Lappi.

Other author	Wiley, Ronald G., 1947-
Other author	Lappi, Douglas A.
Format	Book
Publication Info	Totowa, N.J. : Humana Press, ©2005.
Description	xi, 311 pages : illustrations ; 24 cm
Subjects	Immunotoxins--therapeutic use. Antibodies, Monoclonal--therapeutic use. Cholinergic Fibers--metabolism. Neurobiology--methods. Neurons--pathology.

Contents	Introduction to molecular neurosurgery / Ronald G. Wiley and Douglas A. Lappi -- Ribosome-inactivating proteins / Fiorenzo Stirpe -- Biochemical, physiological, and behavioral characterizations of the cholinergic basal forebrain lesion produced by 192 IgG-saporin / Jerene J. Waite -- Basal forebrain cholinergic lesion by 192 IgG-saporin: a tool to assess the consequences of cortical cholinergic dysfunction in Alzheimers disease / Reinhard Schliebs -- 192 IgG-saporin-induced partial cortical cholinergic deafferentation as a model for determining the interactions between brain aging and neurodevelopmental defects in the cortical cholinergic input system / Martin Sarter and John P. Bruno -- Exploring the role of acetylcholine in primate cognition using Me20.4 IgG-saporin / Rosalind M. Ridley and Harry F. Baker -- Cortical cholinergic deafferentation induces A-beta deposition: towards a physiologic animal model of Alzheimer's disease / Thomas G. Beach ... [et al.] -- Chemical dissection of brain glucoregulatory circuitry / Sue Ritter ... [et al.] -- Cardiovascular deficits after lesions of C1 adrenergic neurons with a saporin-based immunotoxin / Patrice G. Guyenet, Ruth L. Stornetta, and Ann M. Schreihofer -- Saporin conjugates and pain / Ronald G. Wiley and Douglas A. Lappi -- The use of saporin conjugates to dissect neurons responsible for sleep and wakefulness / Carlos Blanco-Centurion ... [et al.] -- Isolectin I-B4-mediated cytotoxic targeting of sensory neurons / Lucy Vulchanova and Christopher N. Honda -- B fragment of cholera toxin conjugated to saporin / Peter T. O'hara, Kanwarjit Kelley, and Luc Jasmin.
Bibliography note	Includes bibliographical references and index.
LCCN	2004016130
ISBN	1588291995 :

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Molecular neurosurgery with targeted toxins / edited by Ronald G. Wiley and Douglas A. Lappi.

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