| Summary |
The effects of a prototype bio-protective natural supplement on antioxidant status and cardiovascular disease risk markers in aerobically trained males. Purpose: The purpose of this investigation was to determine the effects of a prototype bio-protective natural supplement on antioxidant status and cardiovascular disease risk markers, such as blood pressure and blood lipids, in aerobically trained males Methods: Sixteen aerobically trained (> 5 hours of cardiovascular exercise/week) males (age, 30.03 ± 1.71 yr; ht, 70.35±0.58 in: wt, 163.01±5.531bs) were assigned within a double-blind, placebo controlled study. Blood pressure and fasting blood samples (glucose, insulin, lipids) were assessed before and after a 21-day supplementation period. Blood plasma was tested for total antioxidant capacity. Standardized exercise protocols (Treadmill or Lode cycle ergometer) were administered based on participants' training programs. Results: In response to 21 -days of ingesting supplement #39 produced no significant change between groups or over time with respect to antioxidant capacity, HDL, total cholesterol, total cholesterokHDL ratio, triglycerides, resting or exercise blood pressures. Significant changes were seen in plasma glucose (p=0.047). Conclusion: Supplement # 39 does not produce significant changes with respect to blood lipid levels or antioxidant capacity, and thus may not be suitable as a bio-protective supplement against cardiovascular disease. |
