Tools

LEADER 03808ctm a2200577 i 4500

001 ocn170994444;

003 OCoLC;

005 20250120151949.0;

008 070912s2006 xx a bm 000 0 eng d;

035 a| (Sirsi) o170994444;

035 a| (OCoLC)170994444;

049 a| EREE;

050 4 a| QL638.M678b| L32 2006;

100 1 a| LaButti, Kurt Michael,e| author.?| UNAUTHORIZED;

245 10 a| Molecular genetic characterization of the HOXBb cluster from the striped bass, Morone saxatilis /c| by Kurt Michael LaButti.;

264 0 c| 2006.;

300 a| ix, 124 leaves :b| illustrations (some color) ;c| 28 cm;

336 a| textb| txt2| rdacontent;

337 a| unmediatedb| n2| rdamedia;

338 a| volumeb| nc2| rdacarrier;

502 b| M.S.c| East Carolina Universityd| 2006;

500 a| Presented to the faculty of the Department of Biology.;

500 a| Advisor: Edmund J. Stellwag;

520 3 a| This research focused on the recombinant DNA cloning, molecular genetic mapping and bioinformatic characterization of the HoxBb cluster of the striped bass (Morone saxatilis) genome. Molecular characterization of other teleost Hox clusters have shown a depletion of Hox gene content in one sister cluster with respect to the other. Comparative genomic analyses have also revealed conserved non-coding sequences within the intergenic and intron-associated sequence involved in Hox gene regulation. The results of this research revealed complete genes for HoxBlb, B5b, B6b as well as a B3b pseudogene. Comparative genomics of the intergenic and intron-derived sequences to orthologous and paralogous regions from diverse metazoans revealed a collection of seven conserved non-coding sequences. Based on bioinformatic analysis this region was devoid of B2b or B4b genes. This genetic architecture is consistent with previously characterized HoxBh clusters from other teleost species, indicative that the evolution of the HoxBb cluster in teleosts followed a very similar trajectory after its divergence of its sister cluster HoxBa.;

504 a| Includes bibliographical references (leaves 98-103).;

650 0 a| Striped bassx| Genetics.=| ^A69980;

650 0 a| Striped bassx| Genome mapping.=| ^A69980;

650 0 a| Molecular cloning.=| ^A11922;

650 0 a| DNAx| Analysis.=| ^A13543;

650 0 a| Gene mapping.=| ^A137648;

650 0 a| Animal genome mapping.=| ^A587449;

650 7 a| Animal genome mapping.2| fast0| (OCoLC)fst00809204;

650 7 a| DNAx| Analysis.2| fast0| (OCoLC)fst00886556;

650 7 a| Gene mapping.2| fast0| (OCoLC)fst00939625;

650 7 a| Molecular cloning.2| fast0| (OCoLC)fst01024762;

655 7 a| dissertations.2| aat0| (CStmoGRI)aatgf300028029;

655 7 a| Academic theses.2| fast0| (OCoLC)fst01726453;

655 7 a| Academic theses.2| lcgft;

655 7 a| Thèses et écrits académiques.2| rvmgf0| (CaQQLa)RVMGF-000001173;

700 1 a| Stellwag, Edmund J.q| (Edmund Johannes),d| 1951-e| degree supervisor.1| https://id.oclc.org/worldcat/entity/E39PCjxw8WYhVjjbHqyXbxhXMP=| ^A1031239;

710 2 a| East Carolina University.b| Department of Biology.=| ^A637467;

856 41 z| Access via ScholarShipu| http://hdl.handle.net/10342/12558;

949 a| Click on web addressw| asish| joyner101;

949 a| Click on web addressw| asish| hsl111;

994 a| C0b| ERE;

596 a| 1 4;

998 a| 1093226;

999 a| ASK AT SPECIAL COLLECTIONS DESKw| ASISc| 1i| MQ1936433l| JSCJTHDm| JOYNERr| Ys| Yt| JSCJTHDu| 9/12/2007x| ETDz| JSPECCOLLo| .STAFF. 0;

999 a| CLICK ON WEB ADDRESSw| ASISc| 1i| 1093226-3001l| JNETm| JOYNERr| Ys| Yt| JNE3ETDu| 1/14/2025x| ETDz| JERESOURCE;

999 a| CLICK ON WEB ADDRESSw| ASISc| 1i| 1093226-4001l| HSLELECm| HSLr| Ys| Yt| HEETDu| 1/14/2025x| ETDz| HERESOURCE;

Molecular genetic characterization of the HOXBb cluster from the striped bass, Morone saxatilis / by Kurt Michael LaButti.

Author/creator	LaButti, Kurt Michael author.
Other author	Stellwag, Edmund J. (Edmund Johannes), 1951- degree supervisor.
Other author	East Carolina University. Department of Biology.
Format	Theses and dissertations
Production	2006.
Description	ix, 124 leaves : illustrations (some color) ; 28 cm
Supplemental Content	Access via ScholarShip
Subjects	Striped bass--Genetics. Striped bass--Genome mapping. Molecular cloning. DNA--Analysis. Gene mapping. Animal genome mapping.

Summary	This research focused on the recombinant DNA cloning, molecular genetic mapping and bioinformatic characterization of the HoxBb cluster of the striped bass (Morone saxatilis) genome. Molecular characterization of other teleost Hox clusters have shown a depletion of Hox gene content in one sister cluster with respect to the other. Comparative genomic analyses have also revealed conserved non-coding sequences within the intergenic and intron-associated sequence involved in Hox gene regulation. The results of this research revealed complete genes for HoxBlb, B5b, B6b as well as a B3b pseudogene. Comparative genomics of the intergenic and intron-derived sequences to orthologous and paralogous regions from diverse metazoans revealed a collection of seven conserved non-coding sequences. Based on bioinformatic analysis this region was devoid of B2b or B4b genes. This genetic architecture is consistent with previously characterized HoxBh clusters from other teleost species, indicative that the evolution of the HoxBb cluster in teleosts followed a very similar trajectory after its divergence of its sister cluster HoxBa.
General note	Presented to the faculty of the Department of Biology.
General note	Advisor: Edmund J. Stellwag
Dissertation note	M.S. East Carolina University 2006
Bibliography note	Includes bibliographical references (leaves 98-103).
Genre/form	dissertations.
Genre/form	Academic theses.
Genre/form	Academic theses.
Genre/form	Thèses et écrits académiques.

Availability

Library	Location	Call Number	Status	Item Actions
Joyner	University Archives	ASK AT SPECIAL COLLECTIONS DESK	✔ Available	Request Material
	Electronic Resources	Access Content Online	✔ Available

Molecular genetic characterization of the HOXBb cluster from the striped bass, Morone saxatilis / by Kurt Michael LaButti.

Click here for more information about this title

Availability