LEADER 02812cam 2200457Ki 4500001 on1197848453 003 OCoLC 005 20210601105725.0 008 200926s2021 sz 000 0 eng d 020 9783030625641 |qhardcover 020 3030625648 |qhardcover 035 (Sirsi) o1197848453 035 (OCoLC)1197848453 040 YDX |beng |erda |cYDX |dBDX |dOHX |dGZU |dOCLCO |dYDX |dOCLCF |dUtOrBLW 049 EREE 050 4 Q182.3 |b.F73 2021 082 04 507.2 |223 100 1 Franklin, Allan, |d1938- |eauthor. |=^A87544 245 10 Once can be enough : |bdecisive experiments, no replication required / |cAllan Franklin, Ronald Laymon. 264 1 Cham, Switzerland : |bSpringer, |c[2021] 300 xii, 181 pages ; |c25 cm 336 text |btxt |2rdacontent 337 unmediated |bn |2rdamedia 338 volume |bnc |2rdacarrier 504 Includes bibliographical references. 520 There has recently been considerable discussion of a "replication crisis" in some areas of science. In this book, the authors argue that replication is not a necessary criterion for the validation of a scientific experiment. Five episodes from physics and genetics are used to substantiate this thesis: the Meselson-Stahl experiment on DNA replication, the discoveries of the positron and the omega minus hyperon, Mendels plant experiments, and the discovery of parity nonconservation. Two cases in which once wasnt enough are also discussed, the nondiscovery of parity nonconservation and the search for magnetic monopoles. Reasons why once wasnt enough are also discussed. 505 0 Introduction -- The Meselson-Stahl Experiment: "The Most Beautiful Experiment in Biology" -- The Discovery of the Positron -- The Discovery of the Omega Minus Hyperon -- Once Should Have Been Enough: Gregor Mendel, "Experiments in Plant Hybridization" -- Once Came Close To Being Enough: Electron Polarization and Parity Nonconservation -- The Discovery of Parity Nonconservation -- The Search for the Magnetic Monopole -- Conclusion. 650 0 Science |xExperiments |xHistory. |=^A5360 650 0 Replication (Experimental design) |=^A356046 650 7 Replication (Experimental design) |2fast |0(OCoLC)fst01094833 650 7 Science |xExperiments. |2fast |0(OCoLC)fst01108230 655 7 History. |2fast |0(OCoLC)fst01411628 700 1 Laymon, Ronald L., |eauthor. |=^A1421284 938 Otto Harrassowitz |bHARR |nhar205021535 938 Brodart |bBROD |n128075104 938 YBP Library Services |bYANK |n16969203 949 Q182.3 .F73 2021 |hJOYNER48 |ojssb 994 C0 |bERE 596 1 998 5633876