ECU Libraries Catalog

Biologics for early rheumatoid arthritis : review of health economic studies / Espen Movik [and 5 others].

Author/creator Movik, Espen author.
Other author/creatorContained in (work): Movik, Espen. Biologiske legemidler i behandling av tidlig leddgikt (revmatoid artritt)
Other author/creatorNasjonalt kunnskapssenter for helsetjenesten, issuing body.
Format Electronic and Book
Publication Info Oslo : Norwegian Knowledge Centre for the Health Services, February 2011.
Description1 online resource (1 PDF file (6 pages))
Supplemental Content Direct link to resource
Summary It is estimated that 20,000-30,000 people in Norway suffer from the disease. Due to the patients' reduced functional capacity, costs are incurred by employers, relatives and not least the patients themselves. Research has shown that early treatment with biologic drugs may be beneficial. Biologics are however more costly than conventional DMARDs, and Norwegian guidelines therefore stipulate that at least one DMARD should be attempted before treatment with biologic drugs is initiated. The Norwegian Knowledge Centre for the Health Services has reviewed the literature on the cost-effectiveness of biologic treatment for early RA as part of a project commissioned by the commissioned by the Norwegian Rheumatism Association. We searched systematically for health economic evaluations of biologic treatment of patients with early RA (disease duration of three years or less) compared with DMARD treatment. We found six studies, which all incorporated a TNF-inhibitor such as aldalimumab, etanercept or infliximab. No studies on the other biologic drugs were found. Our findings were:1. Treatment with biologic drugs in early RA may be cost-effective, though not necessarily as first-line treatment.2. This is consistent with current Norwegian guidelines which state that treatment with at least one DMARD should be attempted before biologic treatment is initiated.3. Inclusion of indirect costs has a major bearing on the results.4. The study results vary significantly.
General noteEnglish summary excerpted from full report in Norwegian: Biologiske legemidler i behandling av tidlig leddgikt (revmatoid artritt).
General noteExcerpt from Systematic review no. 4-2011.
Access restrictionAccess restricted to subscribing institutions.
Source of descriptionDescription based on online resource; title from PDF title page (viewed July 1, 2019).

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