Antibiotics : actions, origins, resistance

Antibiotics : actions, origins, resistance / by Christopher Walsh.

Author/creator	Walsh, Christopher
Format	Book and Print
Publication Info	Washington, D.C. : ASM Press, ©2003.
Description	x, 335 pages : illustrations (some color) ; 26 cm
Subject(s)	Anti-Bacterial Agents--pharmacology. Drug Resistance, Bacterial.

Contents	Antibiotics : initial concepts -- Introduction to major antibiotic classes and modes of action -- Antibiotics that act on cell wall biosynthesis -- Antibiotics that block bacterial protein biosynthesis -- Antibiotics that block DNA replication and repair : the Quinolones -- Other targets of antibacterial drugs -- Natural and producer immunity versus acquired resistance -- Enzymatic destruction or modification of the antibiotic by resistant bacteria -- Antibiotic resistance by efflux pumps -- Antibiotic resistance by replacement or modification of the antibiotic target -- Regulation of antibiotic biosynthesis in producer organisms -- Polyketide antibiotic biosynthesis : assembly line enzymology -- Enzymatic assembly lines for nonribosomal peptide antibiotics -- Biosynthesis of other classes of antibiotics -- New looks at targets -- New molecules -- Contexts and challenges for the use of new antibiotics.
Bibliography note	Includes bibliographical references (p. 297-328) and index.
LCCN	2002152389
ISBN	1555812546 :

Library	Location	Call Number	Status	Item Actions